PHYTOCHEMICAL ANALYSIS AND ANTI-BACTERIAL SCREENING OF Ajuga iva L. EXTRACT FROM ALGERIA

Abstract

ABSTRACT. The objectives assigned to the present study are the phytochemical screening of several secondary metabolites and the evaluation of the antibacterial activity of the methanolic extracts of the different organs of Ajuga iva L. Phytochemical screening revealed the presence of substances with high therapeutic values ​​(flavonoids, tannins, polyphenols, coumarin, etc.). The antibacterial activity of the extracts is carried out by the diffusion method on agar medium vis-à-vis twenty-three bacterial strains chosen according to the traditional use of this species in Algeria: Bacillus cereus, Escherichia coli (ATCC22), Escherichia coli (BLSE), Escherichia coli (ciproR), Escherichia coli (mcr1), Klebsiella pneumoniae (C+), Klebsiella pneumoniae (C-), Klebsiella pneumoniae Nassey Marseille, Serratia sp, Salmonella sp, Pseudomonas aeruginosa (ATCC53), Pseudomonas sp, Pseudomonas aeruginosa (VIM21), Pseudomonas aeruginosa (VIM22), Acinetobacter (NDM1), Acinetobacter (OXA23), Staphylococcus aureus, Staphylococcus aureus (23), Staphylococcus aureus (13), Enterobacter cloacae (FOSR1), Enterobacter cloacae (FOSR2), Enterococcus faecalis (Vanc R), Enterococcus faecalis (ATCC12). The study shows a remarkable antibacterial activity against all the microbial strains tested with the exception of Enterobacter cloacae (FOSR1).